Event Information

Event Topic:
Updated BIONews plus live Presentation – What do multi-omics, bonding parts, and cell sorting have in common? Ultrasound!

Event Description:
Ultrasound is used in a myriad of places to generate mechanical, chemical or biological effects. Low amplitudes generate gentle effects, while high intensity focused ultrasound can lead to dramatic heating or damage to even hardened metals. Here we will focus on 3 novel use cases: 1) In multi-omics, ultrasound lyses cells, and can fragment DNA or chromatin down to a hundred or so base pairs. It’s the cavitation bubbles that amplify acoustic energy down to small spatial and temporal scales. But cavitation is stochastic, and can generate inconsistent results. I will discuss our way of improving consistency. 2) In manufacturing, oven-curing adhesives can damage li-ion batteries and other heat sensitive components. Focused ultrasound can spot-cure epoxies locally without damaging nearby components. First proof of concept studies will be discussed. Finally, 3) the workhorses of cell sorting are FACS and MACS. We will present an alternative method that combines the best of both, using, what else? – ultrasound!

Date/Time:
Date(s) - 03/11/25
6:15 pm - 8:15 pm

Event Location:
Zoom talk: https://us02web.zoom.us/j/89077658197:

Speaker Information

Event Speaker:
Thomas Matula, PhD

Event Speaker Title:
President & CEO

Event Speaker Company:
Matchstick Technologies, Inc.

Event Speaker Bio:

Tom Matula received his PhD in Physics from Washington State University in 1993 before joining the Applied Physics Lab (APL) at the University of Washington, Seattle. In 1997 he received the DOE Defense Programs Young Scientist and Engineer Award, and Presidential Early Career Award (PECASE). He helped create the NASA Parabolic flight opportunities program that is run out of Houston, TX. He is a Fellow of the Acoustical Society of America, Senior member of the IEEE, and is the Director of the Center for Industrial and Medical Ultrasound (CIMU). He has over a dozen granted patents. Much of his work focuses on ultrasound-induced effects in liquids and solids. One of his inventions was spun off as a startup company, which now manufactures sample processing instruments for multi-omics. In his scientific roles, he is interested in projects that vertically integrate mechanistic studies with prototype development and translational activities.

Event Details

Cost:
$0

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