Join B2DG members and guests for our May 12th evening meeting as we cover updated Weekly BIONews, followed by a video entitled: BEYOND INHERITANCE – We are all Genetic Mosaics.
Roxanne Khamsi
Medical Correspondent, The Atlantic
6:15 – 6:30 PM PDT – Preslides and networking
6:30 – 7:10 PM – Weekly Updated BIONews
7:10 – 8:30 PM Video followed by Discussion and Networking
Eric Topol and Roxanne Khamsi explore how our trillions of cells acquire, on average, a new mutation daily—a concept known as “genetic mosaicism.”These somatic mutations drive “endoevolution,” impacting health and disease. The discussion emphasizes that we are constantly evolving at a cellular level, which profoundly influences our health beyond the DNA we inherit at conception
Key Concepts from the Discussion:
Beyond Inheritance: While inherited genes are significant, Khamsi argues that the mutations our cells acquire throughout our lives—the somatic mutations—are equally critical for understanding health and diseases.
The Mosaic Body: Our bodies are not uniform, but rather a “mosaic” of cells with differing genetic codes, resulting in trillions of mutations per day throughout the body’s ~37 trillion cells.
Endoevolution: A process of “Darwinian selection” occurs internally, where certain mutated cells outcompete others (cellular competition), a concept linked to Wilhelm Roux’s 1881 work The Struggle of Parts
Environmental Impact: Factors like UV light, pollution, and plastics can accelerate these somatic mutations.
Significance of Single-Cell Technology: Advancements in single-cell sequencing allow scientists to see these cellular mutations more clearly, shedding light on cancer development and aging.
Event Information
Event Topic:
Updated BIONews and video Beyond Inheritance – We are all Genetic Mosaics.
Event Description:
Date/Time:
Date(s) - 05/12/26
6:15 pm - 8:30 pm
Event Location:
Zoom talk: https://us02web.zoom.us/j/83593256859:
Speaker Information
Event Speaker:
Harry Wachob, PhD
Event Speaker Title:
President and Founder
Event Speaker Company:
Bio2Device Group
Event Speaker Bio:
Event Details
Cost:
$0
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