Missing menopause in basic research – risk factors in Alzheimer’s disease

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Join our B2DG members and guests as we meet on March 10 at 6:15 PM PST to cover the weekly updated BIONews and then the live presentation – “Missing menopause in basic research – risk factors in Alzheimer’s disease” by Prof. Nozomi Nishimura.

Event Information

Event Topic:
Missing menopause in basic research – risk factors in Alzheimer’s disease

Event Description:
In the past, basic science research on Alzheimer’s disease rarely addressed sex differences, and the biology of menopause was mostly ignored. We developed a new mouse model of Alzheimer’s disease based on ApoE4 genotype and high blood pressure that includes menopausal transition. Using two-photon microscopy, we imaged blood flow deficits in the brain that are linked to cognitive symptoms. However, males and females responded differently to experimental treatments, suggesting that including menopausal females in studies is vital for finding future drugs.

Date/Time:
Date(s) - 03/10/26
6:15 pm - 8:30 pm

Event Location:
Zoom talk: https://us02web.zoom.us/j/83593256859:

Speaker Information

Event Speaker:
Nozomi Nishimura

Event Speaker Title:
Associate Professor, Meinig School of Biomedical Engineering and Director of the Menopause Health Engineering Initiative

Event Speaker Company:
Cornell University.

Event Speaker Bio:
Missing menopause in basic research – risk factors in Alzheimer’s disease
Nozomi Nishimura is an Associate Professor in the Meinig School of Biomedical Engineering and Director of the Menopause Health Engineering Initiative at Cornell University. She develops optical tools for studying in vivo cell behaviors in disease. To study the actions of cells, her lab develops intravital multiphoton microscopy imaging methods that reveal how cells function, move, and interact within the body. She applies these tools in many systems but has particular interests in studying the effects of microvascular dysfunction in the brain. Her lab studies the role of microvascular occlusions in Alzheimer’s disease and neurodegeneration. These methods were recently adapted for the beating mouse heart, providing new capabilities to study single-cell function and cardiac microvasculature. She was awarded an NSF CAREER Award, is a Fellow of the American Institute of Medical and Biological Engineering (AIMBE), won the Cook Award for commitment to women’s issues and improving the climate for women at Cornell, and the James M. and Marsha D. McCormick Award for Outstanding Advising of First-Year Engineering Students in Cornell Engineering. She is highly active in Diversity, Equity, and Inclusion committees at the college and department level.

Event Details

Cost:
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