Solving the Challenges of DNA Sequencing for Molecular Diagnostics-Stefan Roever-04/03/2012 - 8:30am

Event Information
Event Topic: 
Solving the Challenges of DNA Sequencing for Molecular Diagnostics
Event Date: 
04/03/2012 - 8:30am
Event Location: 
Sunnyvale City Council Chambers, 456 West Olive Ave., Sunnyale, CA
Speaker Information
Event Speaker: 
Stefan Roever
Event Speaker Title: 
CEO & Founder
Event Speaker Company: 
Genia Technologies, Inc
Event Speaker Bio: 

Stefan Roever

Stefan Roever has a broad entrepreneurial, software, and finance background. He was Co-Founder and CEO of Brokat Technologies, an encryption banking software company. Brokat reached a several billion dollar market cap and went public in 1998 on the Frankfurt Stock Exchange and on NASDAQ in 2000. Mr. Roever was honored with the Ernst and Young Entrepreneur of the Year Award in Germany. He is an active private equity investor and currently serves as Chairman of WRS Materials, a roll-up of wafer reclaim companies. Mr. Roever also is a two time award holder of Technology Pioneer by the World Economic Forum. He earned degrees in both economics and law from the University of Tuebingen.

Event Details
Event Details: 

There is no debate that genetic information is needed to truly realize the promise of personalized medicine. The problem is that today’s DNA sequencers cost anywhere from $50K - $1M, rely on complicated optics, and utilize a complex workflow that does not lend itself to clinical utility.
Genia is using standard semiconductor technology to enable massively parallel, single molecule DNA sequencing. The company has developed a versatile nanopore-based platform which allows for single molecule, electrical, real-time analysis without the need for enzymes, complicated optics, labels, amplification, or fluidics. Genia’s key proprietary innovations around the nanopore allow single molecules of single stranded DNA to move through the pore slowly so the sequence can be measured accurately. The sensor itself is truly transformative and allows very small electrical signals (~0.2 pA current levels) to be seen high above the noise floor, which is one of the issues other nanopore companies are currently struggling with. The data shows that with highly accurate analog electronics and clever data analysis techniques, single base discrimination is possible, and adequate SNR can be reached to perform DNA sequencing.
Genia’s mission is to unify Moore’s Law with biotechnology to make genetic information universally available. By developing a true integrated circuit on standard semiconductor process technology, Genia brings Moore’s Law to the biological world to revolutionize the world of DNA sequencing.